The star has given the entirety of his £25k award prize money to the MVT, which works to save the UK's independent live music spots.
He was presented with the prize on mid-October as his latest record his work was named the best record of the last 12 months.
The musician has decided to donate the funds to the Music Venues Trust, in acknowledgment of the vital role local spots had in his early career.
"I wouldn't be doing this success if it weren't for all the performances I did around the North East, and further afield, when I was beginning," said Fender. "These venues are legendary, but they are struggling."
Since the start of 2023, at least 150 of these venues have ceased operations – roughly one-sixth of the entire UK sector.
Recently, well-known musicians like Pulp, Coldplay, Katy Perry and Ed Sheeran have all backed the Music Venues Trust in its attempts to help venues survive, by applying a modest fee to their ticket prices, which goes to help local stages.
Sam Fender also joined in, generating in excess of £100,000 on his live tour to support 38 small stages across the UK.
The donation assisted venues that were facing possible closure due to issues arising from water damage, blazes and bereavements, as well as licensing issues, court cases and neighbor objections.
Some locations obtained funding support in improving amenities and sound and lighting systems that helped musicians and audiences.
"The idea that funds from shows in major spaces supports the local stages, where it all starts for musicians like me, is just sensible," the star has commented.
He is among several artists to give his Mercury Prize prize money to good deeds.
Back when they earned the trophy in the mid-90s for their record the album, lead singer Jarvis Cocker stated that the band would give their winnings to the non-profit War Child.
That year, rapper and singer she split her bounty among multiple charities, including the NSPCC and a charity for Sickle Cell.
"I also donated a grand to Highgate Newtown, to their gymnastics program, because I practiced gymnastics when I was growing up and they lacked better apparatus," the artist told a publication.
In recent years, the band donated their prize money to the local youth club that supported their band, in addition to other independent music bodies.
Also 1994 winners the group donated their award to a MS organization after a friend was identified with the condition.
"The victory was sufficient," stated artist Small. "The money was the extra but we could do without the cherry, because we had the honor. So our winning impacted somebody else's life."
Recently, the trust revealed it had saved two small stages in the South East, by bringing them into public stewardship.
The Joiners in that area and the second in that location were purchased under the public acquisition program, which is backed by the arts council and supporters who buy "stakes" in the venues.
